BFTT-PES-1 TFF-cassette

BFTT-PES-1: Reusable PES TFF Cassette

The BFTT-PES-1 is a reusable membrane cassette with a polyethersulfone (PES) membrane for tangential flow filtration (TFF). This technique, also known as crossflow filtration, is used to concentrate liquids and perform diafiltration, for example for buffer exchange.

During tangential flow filtration, the liquid flows along the membrane surface. Part of the liquid passes through the membrane as permeate, while retained components remain in the retentate. The selected cut-off helps determine which components are retained and which can pass through the membrane.

Twelve Cut-Off Options from 1 to 1000 kDa

The BFTT-PES-1 is available with the following molecular weight cut-off (MWCO) values: 1, 3, 5, 8, 10, 30, 50, 100, 300, 500 and 1000 kDa. Both 100S and 100L versions are available at 100 kDa.

The appropriate cut-off depends on the components you want to retain, the composition of your liquid and the required separation.

Seven Effective Membrane Areas

The BFTT-PES-1 is available in the following effective membrane areas:

• 0.01 m² — 100 cm²
• 0.02 m² — 200 cm²
• 0.11 m²
• 0.46 m²
• 0.50 m²
• 2.33 m²
• 2.50 m²

The required membrane area depends on factors such as process volume, liquid properties and target processing time.

Screen and Body Configurations

The BFTT-PES-1 product range includes three screen options:

• A – Tight screen
• C – Standard coarse screen
• V – Suspended screen

Two body options are available: S – Standard body and B – Flow B. Available combinations of screen, membrane area and body vary by configuration. Not all options can be combined.

Concentration and Diafiltration

During concentration, liquid passes through the membrane, increasing the concentration of retained components. Diafiltration is used for buffer exchange or the removal of small components that can pass through the membrane.

To select a suitable cassette, the PES membrane, cut-off, effective membrane area and screen configuration should match your application and process conditions.

Advice from Van Borselen Filters

Are you looking for a reusable PES TFF cassette for your process? The specialists at Van Borselen Filters help you select a suitable BFTT-PES-1.

Contact us for advice on the appropriate cut-off, membrane area and available screen and body configurations.