BFTT-RC-2 TFF-cassette

BFTT-RC-2: RC TFF Cassette with Polyurethane Construction

The BFTT-RC-2 is a membrane cassette with a regenerated cellulose (RC) membrane in a polyurethane construction for tangential flow filtration (TFF). This technique, also known as crossflow filtration, is used to concentrate liquids and perform diafiltration, for example for buffer exchange.

During tangential flow filtration, the liquid flows along the membrane surface. Part of the liquid passes through the membrane as permeate, while retained components remain in the retentate. The selected cut-off helps determine which components are retained and which can pass through the membrane.

Fifteen Cut-Off Options from 1 to 300 kDa

The BFTT-RC-2 product range includes the following molecular weight cut-off (MWCO) values: 1, 2, 3, 5, 8, 10, 30, 50, 100 and 300 kDa.

In addition to the S versions, specific H and L versions are available:

• 1 kDa: 001S and 001H
• 3 kDa: 003S, 003H and 003L
• 30 kDa: 030S and 030H
• 100 kDa: 100S and 100H

The appropriate membrane version and cut-off are selected based on your application, the components you want to retain and the required separation.

Five Effective Membrane Areas

The BFTT-RC-2 is available in the following effective membrane areas:

• 0.01 m² — 100 cm²
• 0.02 m² — 200 cm²
• 0.11 m²
• 0.50 m²
• 2.50 m²

The required membrane area depends on factors such as process volume, liquid properties and target processing time.

Four Screen Configurations

The BFTT-RC-2 product range includes four screen options:

• A – Tight screen
• C – Standard coarse screen
• D – Coarse screen
• V – Suspended screen

The cassette is offered with an S – Standard body. Available combinations of cut-off, screen and membrane area vary by configuration. Not all options can be combined.

Concentration and Diafiltration

During concentration, liquid passes through the membrane, increasing the concentration of retained components. Diafiltration is used for buffer exchange or the removal of small components that can pass through the membrane.

To select a suitable TFF cassette, the RC membrane, cut-off, effective membrane area and screen configuration should match your liquid and process conditions.

Advice from Van Borselen Filters

Van Borselen Filters helps you select a BFTT-RC-2 TFF cassette that fits your filtration process. Our specialists discuss your liquid, process volume and required separation with you.

Contact us for advice on the appropriate cut-off, membrane area and available screen configuration.