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What is the Water Intrusion Test and when is it used?
The Water Intrusion Test verifies the integrity of hydrophobic PTFE membrane filters by measuring water intrusion under pressure in sterile GMP applications.
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Diffusive Flow Test (DFT): reliable integrity test
The Diffusive Flow Test (DFT) is a non-destructive integrity test for hydrophilic membrane filters, such as 0.2 µm PES filters. By measuring gas diffusion below the bubble point pressure, it confirms whether the filter is intact. A critical test for sterile filtration in GMP environments.
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What is bubble point testing? Purpose & Applications
Bubble point testing verifies the integrity of membrane filters by measuring the pressure at which gas bubbles first appear, which is indicative of the pore size in pharmaceutical and biotechnological processes.
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What is sterile filtration and when is a filter truly sterile?
Sterile filtration removes microorganisms without affecting product quality; only 0.2 µm filters that retain 10⁷ CFU of Brevundimonas diminuta in accordance with ASTM F838 are considered sterile.
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Absolute vs. nominal: how to select the right filter for your application
This blog explains differences between absolute and nominal filters, efficiency, selection, and why filters and integrity testing are essential for sterile pharma and biotech.
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Porous sintered metal: maximum performance under extreme operating conditions
Porous sintered metal delivers reliable filtration under extreme temperatures, pressure and chemicals, combining durability and consistent performance for demanding industrial applications.
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Reusing Chocolate with SWECO: The Preferred Solution for 90% of Belgian Chocolatiers
Chocolate is more expensive than ever. That’s why it’s essential to prevent waste. With the right screening technology, you can easily recover off-spec product and increase your yield – even as a small-scale chocolatier. Discover how SWECO helps you get more out of your chocolate production process.
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The best optimizations for your dairy production process
Filtratie is onmisbaar in elke stap van het kaasproductieproces – van wei- en luchtfiltratie tot het zuiveren van water en zoutbaden. In deze blog leest u welke filtratietechnieken er zijn en welke oplossingen Van Borselen Filters hiervoor biedt.
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What is PUPSIT and how does it strengthen filter integrity?
PUPSIT (Pre-Use/Post Sterilisation Integrity Testing) is essential for ensuring the integrity of sterilizing filters in the biotechnology and pharmaceutical industries. In this blog, we explain what PUPSIT is, how it works, and the benefits it offers for maintaining sterility assurance in your processes.
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Are sterile filters reusable?
This blog helps evaluate whether reusing sterile filters is cost-effective, highlighting risks, validation requirements, hidden costs and viable alternatives for reliable sterile filtration.
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